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an Hsp90 inhibitor
Smiles: CN1C(C(C)C)=C(NC(=O)NC2C=CC(Cl)=CC=2)C(=O)N1C1C=CC=CC=1
InChi: InChI=1S/C11H15N5O5/c1-20-7-6(18)4(2-17)21-10(7)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4
is detected
The inhibition of proteasome was through specific inhibition of chymotrypsin-like activity of the proteasome
RORγt Inverse agonist 6 xerol an Hsp90 inhibitorRORt Inverse agonist 6 (compound 43) is a RORt inverse agonist for the study of Th17 driven autoimmune diseases. RORt Inverse agonist 6 (compound 43) suppresses IL 17A gene expression by IL 23 stimulation in vivo. Product information CAS Number: 1887161 80 9 Molecular Weight: 565. 02 Formula: C28H29ClN6O5 Chemical Name: 6 ({2 [(3 chloro 4 cyanophenyl)carbamoyl]morpholine 4 carbonyl}amino) 3 (cyclopropylmethyl) 2,4 dioxo 1 (propan 2 yl) 2,3,4,4a