RMC-3943 6243 InChi: InChI=1S/C19H15Cl2N3O2/c1-12-10-18(26-24-12)17(11-22-15-6-2-13(20)3-7-15)19(25)23-16-8-4-14(21)5-9-16/h2-11

InChi: InChI=1S/C19H15Cl2N3O2/c1-12-10-18(26-24-12)17(11-22-15-6-2-13(20)3-7-15)19(25)23-16-8-4-14(21)5-9-16/h2-11

InChiKey: IKUFKDGKRLMXEX-UHFFFAOYSA-N

γ-Secretase modulator 4 is a potent γ-secretase modulator

Smiles: CC1CCC=C(C)CC2OC=C(C)C=2CC=1 |c:16

24 hours) inhibits interleukin-1β-stimulated nitrite production by vascular smooth muscle cells in a dose-dependent manner

RMC-3943 6243 InChi: InChI=1S/C19H15Cl2N3O2/c1-12-10-18(26-24-12)17(11-22-15-6-2-13(20)3-7-15)19(25)23-16-8-4-14(21)5-9-16/h2-11RMC 3943 is an allosteric SHP2 inhibitor (inhibition of full length SHP2 in biochemical assay, IC50 = 2. 19 nM). Product information CAS Number: 1801764 60 2 Molecular Weight: 425. 38 Formula: C18H22Cl2N6S Chemical Name: (1R) 8 {6 amino 5 [(2, 3 dichloropyridin 4 yl)sulfanyl]pyrazin 2 yl} 8 azaspiro[4. 5]decan 1 amine Smiles: NC1=NC(=CN=C1SC1=CC=NC(Cl)=C1Cl)N1CCC2(CCC[C@H]2N)CC1 InChiKey: PSKJCIJLNDJVDV GFCCVEGCSA N InChi: InChI=1S C18H22Cl2N6S c19 14