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(Rac)-Calpain Inhibitor XII inib bromide Formula: C15H23N3O4S

SKU: 25841508155

4.8
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Description

Formula: C15H23N3O4S

2018 Dec 21

50 uM/20 uM compound concentration's inhibitory percentage are 75%/67% for chitinase/N- acetyl-hexosaminidase respectively

5)1(6)7/h12-13

RITA (1 μM) stabilizes p53 by inhibiting p53/E6AP interaction

(Rac)-Calpain Inhibitor XII inib bromide Formula: C15H23N3O4S(Rac) Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I ( calpain, Ki=19 nM). (Rac) Calpain Inhibitor XII has lower affinities for calpain II (m calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac) Calpain Inhibitor XII has the potential for studying the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury. Product information CAS Number: 181769 57 3

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