Osimertinib dimesylate (AZD-9291 dimesylate) is an irreversible and mutant selective EGFR inhibitor with IC50s of 12 and 1 nM against EGFRL858R and EGFRL858R/T790M
has been used for cancer therapy due to its desirable metabolic stability and less adverse effect
Formula: C24H33N5O4S
Guanylyl cyclase inhibitors NS2028 and ODQ and protein kinase G (PKG) inhibitor KT5823 trigger apoptotic DNA fragmentation in immortalized uterine epithelial cells: anti-apoptotic effects of basal cGMP/PKG
WNK-IN-11 D3 shows trends toward reduction of blood pressure
Creatine monohydrate 5884 hydrochloride Osimertinib dimesylate (AZD-9291 dimesylate) isCreatine monohydrate, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain. Product information CAS Number: 6020 87 7 Molecular Weight: 149. 15 Formula: C4H11N3O3 Chemical Name: 2 (N methylcarbamimidamido)acetic acid hydrate Smiles: O. CN(CC(O)=O)C(N)=N InChiKey: MEJYXFHCRXAUIL UHFFFAOYSA N InChi: InChI=1S C4H9N3O2. H2O c1 7(4(5)6)2 3(8)9; h2H2,1H3,(H3,5,6)(H,8,9); 1H2 Technical Data