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AC-55541 was stable to metabolism by liver microsomes and maintained sustained exposure in rats
TEPP-46 (ML265)
It acts to stabilize HIF-1α expression at normal oxygen tensions in cultured cells
Molecular Weight: 351
TUG-770 exhibits lower potency on the rodent orthologs (mFFA1
IOX1 - 2OG Oxygenases Inhibitor. CAS# 5852-78-8 Catalog No.:M60195-10S AC-55541 was stable to metabolismIOX1, CAS No. 5852 78 8, is a cell permeable broad spectrum inhibitor of most 2OG oxygenases. It inhibits histone demethylase JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX with IC50 at 0. 12, 0. 17, 0. 2, 0. 3, 0. 6 and 1 M respectively. IOX1 inhibits JMJD2A mediated H3K9me3 demethylation in HeLa cells. Product information CAS Number: 5852 78 8 Molecular Weight: 189. 17 Formula: C10H7NO3 Chemical Name: 8 hydroxyquinoline 5 carboxylic acid Smiles:
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