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PF-04979064 exhibited excellent in vitro potency
InChi: InChI=1S/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H
the 50 mg/kg dose was decreased to 30 mg/kg
Identification of a novel series of BET family bromodomain inhibitors: binding mode and profile of I-BET151 (GSK1210151A)
6-maleimidohexanoic acid active esters
S3I-201 - CAS# 501919-59-1 60153 PF-04979064 exhibited excellent in vitroS3I 201, also known as NSC 74859, CAS No. 501919 59 1, is a cell permeable Stat3 inhibitor that binds to the Stat3 SH2 domain, prevents Stat3 phosphorylation activation, dimerization, and DNA binding. Product information CAS Number: 501919 59 1 Molecular Weight: 365. 36 Formula: C16H15NO7S Synonym: NSC 74859 Chemical Name: 2 hydroxy 4 (2 (tosyloxy)acetamido)benzoic acid Smiles: CC1C=CC(=CC=1)S(=O)(=O)OCC(=O)NC1=CC(O)=C(C=C1)C(O)=O InChiKey: