GO-6976 - CAS# 136194-77-9 10001 Giurcaneanu C

Giurcaneanu C

It is now in Phase I clinical trials targeting several advanced or metastatic solid tumors

4 log10 CFU

3-d]pyrimidin-2-yl)-2-methyl-1H-indole-4-carboxamide

AEB071 (sotrastaurin) does not exhibit toxic effects on human islets in vitro

GO-6976 - CAS# 136194-77-9 10001 Giurcaneanu CGO 6976, CAS No. 136194 77 9, also known as PD 406976, is a potent inhibitor of neurotrophin receptor intrinsic tyrosine kinase. GO 6976 blocked neurotrophin induced signaling and autophosphorylation of neurotrophin specific tyrosine kinase (Trk) receptors, either Trk B in cortical neurons or Trk A in GT1 1 trk9 cells. Product information CAS Number: 136194 77 9 Molecular Weight: 378. 43 Formula: C24H18N4O Synonym: PD406976 Chemical Name: 3 (13 methyl