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RK-33 has no effect on either mitochondrial respiration or ATP generation
Formula: C8H14ClN5O4
CAS Number: 2377858-38-1
PPARδ (30
Solubility: DMSO : ≥ 60 mg/mL (138
AZD 5153 Catalog No.:M22444-C RK-33 has no effect onTarget: BRD4 IC50: 5 nM AZD5153 is a potent, selective, and orally available inhibitor of the bromodomain and extraterminal (BET) protein BRD4, with the IC50 value of 5 nM. AZD5153 could simultaneously ligate two bromodomains in BRD4, and exert antitumor activity in multiple xenograft tumor models . In Vitro: A quantitative immuno fluorescent assay in U2OS cells revealed that AZD5153 could significantly disrupt BRD4 foci, with the IC50 value of 1. 7
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