Lefamulin acetate Catalog No.:M19291-C G-5555 inhibits phosphorylation of the

G-5555 inhibits phosphorylation of the PAK1/2 downstream substrate mitogen-activated protein kinase 1 (MEK1) S298 and

Chemical Name: (3R)-4-amino-3-(4-chlorophenyl)butanoic acid hydrochloride

322(2):131-3

3-d]pyrimidin-5-yl)indolin-1-yl)-2-(3-(trifluoromethyl)phenyl)ethanone

69(2):597-607

Lefamulin acetate Catalog No.:M19291-C G-5555 inhibits phosphorylation of theLefamulin acetate (BC 3781 acetate) is an orally active antibiotic for community acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate (BC 3781 acetate) is the first semi synthetic pleuromutilin for systemic treatment of bacterial infections in humans. Lefamulin acetate (BC 3781 acetate) inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, preventing the binding of transfer RNA for peptide