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(1S, 2S)-Bortezomib Size:Contact [email protected] for quotation Formula: C12H14N2

SKU: 54690809568

4.5
USD119.00 USD163.00

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Description

Formula: C12H14N2

is a potent and allosteric activator of AMP-activated protein kinase (AMPK)

In mouse splenocytes and a mouse ICAM-1 expressing cell lines

first Glibenclamide (1 mg/kg/15 min) and then U-89232 (3 mg/kg/15 min) are infused before the 60 min of ischemia

InChiKey: CPMGENCTAWBLNW-UHFFFAOYSA-N

(1S, 2S)-Bortezomib Size:Contact [email protected] for quotation Formula: C12H14N2(1S,2S) Bortezomib is an enantiomer of Bortezomib. Bortezomib is a cell permeable, reversible, and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki of 0. 6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF B. Bortezomib is an anti cancer agent and the first therapeutic proteasome inhibitor to be used in humans. Product information CAS Number: 1132709 14 8 Molecular

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