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GGTI-286 soindolinone-NH-PEG2-COOH The mevalonate coordinates energy input

SKU: 59208209016

4.1
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Description

The mevalonate coordinates energy input and cell proliferation

InChi: InChI=1S/C16H15BrClNO3S2/c1-22-15-7-2-11(10-14(15)17)16-19(8-9-23-16)24(20

7-dihydroxy-2-(2-hydroxyphenyl)-8-[(2R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl]-3

HJB97 (10-1000 nM

Smiles: N[C@@H](CCCCNCC(=O)[C@@H](O)[C@H](O)[C@H](O)CO)C(O)=O

GGTI-286 soindolinone-NH-PEG2-COOH The mevalonate coordinates energy inputGGTI 286 is a cell permeable and potent inhibitor of geranylgeranyltransferase I (GGTase I) that selectively inhibits geranylgeranylation of Rap1A over farnesylation of H Ras in NIH3T3 cells (IC50s = 2 and >30 M, respectively). Product information CAS Number: 171744 11 9 Molecular Weight: 429. 58 Formula: C23H31N3O3S Chemical Name: methyl (2S) 2 [[4 [[(2R) 2 amino 3 sulfanylpropyl]amino] 2 phenylbenzoyl]amino] 4 methylpentanoate Smiles:

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