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Chemical Name: 5-nitro-N-{8-oxatricyclo[7
Solubility: DMSO 100 mg/mL (200
MCC950 reduces Interleukin-1p (IL-1β) production and attenuates the severity of experimental autoimmune encephalomyelitis (EAE)
The selectivity studies using the 308 kinases reveals >120-fold selectivity of Simurosertib (TAK-931) for CDC7 kinase inhibition compared to other kinase inhibitions
gov/books/NBK548874/ PubMed PMID: 31644181
AH 23848 (calcium salt) Size:Contact [email protected] for quotation Chemical Name: 5-nitro-N-{8-oxatricyclo[7AH 23848 (calcium salt) is a dual antagonist of TP1 and EP4 receptors . The thromboxane receptor (TP), also known as the prostanoid TP receptor, is activated by thromboxane A2 (TXA2). TXA2 is an exceptionally potent inducer of platelet aggregation and of contraction of vascular and respiratory smooth muscle . Prostaglandin E2 (PGE2) subtype receptors (EP) are involved in cellular proliferation and tumor development. Prostaglandin E2 (PGE2) activates
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