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PubMed PMID: 26032411
82 fold shift)
small molecule
InChi: InChI=1S/C25H25ClN6O4S/c1-25(2
HAT Inhibitor II
K-115 free base Size:Solid 10 mg PubMed PMID: 26032411Ripasudil free base (K 115 free base) is a specific inhibitor of ROCK, with IC50s of 19 and 51 nM for ROCK2 and ROCK1, respectively. Product information CAS Number: 223645 67 8 Molecular Weight: 323. 39 Formula: C15H18FN3O2S Synonym: Ripasudil free base K 115 free base K115 free base Chemical Name: 4 fluoro 5 {[(2S) 2 methyl 1,4 diazepan 1 yl]sulfonyl}isoquinoline Smiles: C[C@H]1CNCCCN1S(=O)(=O)C1=CC=CC2=CN=CC(F)=C21 InChiKey: QSKQVZWVLOIIEV
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