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InChi: InChI=1S/C16H13FN2O2/c17-12-4-5-14-11(7-12)8-15(19-14)16(21)18-9-10-2-1-3-13(20)6-10/h1-8
Takeuchi K
induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1
A839977 is a P2X7R antagonist
Solubility: DMSO: 71 mg/mL (185
Huwentoxin-IV - CAS# 526224-73-7 6592 InChi: InChI=1S/C16H13FN2O2/c17-12-4-5-14-11(7-12)8-15(19-14)16(21)18-9-10-2-1-3-13(20)6-10/h1-8Huwentoxin IV is a potent and selective sodium channel blocker, inhibits neuronal Nav1. 7, Nav1. 2, Nav1. 3 and Nav1. 4 with IC50s of 26, 150, 338 and 400 nM, respectively. Huwentoxin IV preferentially blocks peripheral nerve subtype Nav1. 7 by binding neurotoxin receptor site 4. Huwentoxin IV has analgesic effects on animal models of inflammatory and neuropathic pain. Product information CAS Number: 526224 73 7 Molecular Weight: 4106. 78 Formula:
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