4 μM in cell adhesion studies assessing the human melanoma M21 or UCLA-P3 human lung carcinoma cell lines
CAS Number: 941685-37-6
AZD5582 results in cIAP1 degradation and caspase-3 cleavage within tumor cells and causes substantial tumor regressions following two weekly doses of 3
InChiKey: INGSNVSERUZOAK-UHFFFAOYSA-N
InChi: InChI=1S/C15H9Cl2F3/c16-13-7-11(8-14(17)9-13)2-1-10-3-5-12(6-4-10)15(18
Leptomycin B Size:Contact [email protected] for quotation 4 μM in cell adhesionLeptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1 exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Product information CAS Number: 87081 35 4 Molecular Weight: 540. 73 Formula: C33H48O6 Chemical Name: (2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E) 17 ethyl 6 hydroxy 3,5,7,9,11,15 hexamethyl 19 [(2S,3S) 3