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ATP-competitive pan-JNK inhibitor that decreases hepatic necrosis and apoptosis
CAS Number: 209808-47-9
Smiles: CC(C)(CC1CC2=CC=CC=C2C1)NC[C@@H](O)COC1=CC(CCC(O)=O)=CC=C1C#N
Escin IA is a triterpene saponin isolated from horse chestnut
Diphenylterazine injections into untransfected BALB/c mice do not yield any background emission
Z-VDVAD-FMK 21843 ATP-competitive pan-JNK inhibitor that decreasesJurkat T lymphocytes treated with an irreversible caspase 2 inhibitor, benzyloxycarbonyl Val Asp(OMe) Val Ala Asp(OMe) fluoromethyl ketone (Z VDVAD FMK), or stably transfected with pro caspase 2 antisense (Casp 2 AS) are refractory to cytochrome c release stimulated by etoposide1. When etoposide induced activation of pro caspase 2 is subverted by Z VDVAD FMK or stable transfection of pro caspase 2 antisense, cytochrome c release and other
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