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Sitagliptin-d4 phosphate 15528 Rocagloic acid shows selective cytotoxicity

SKU: 69268146376

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Description

Rocagloic acid shows selective cytotoxicity against NCI-H187 cell line with an ED50 of 0

Upon intravenous administration and oral administration of Senecionine and Adonifoline

a cell- surface transmembrane glycoprotein of the cadherin superfamily of proteins involved in calcium-mediated cell-cell adhesion and signaling mechanisms

but with no such inhibition on MDA-MB-468 (IC50

K/c1-20-9-5-15(23)13-14(20)3-4-16-17(20)6-10-21(2)18(16)7-11-22(21

Sitagliptin-d4 phosphate 15528 Rocagloic acid shows selective cytotoxicitySitagliptin d4 (MK 0431 d4) phosphate is the deuterium labeled Sitagliptin phosphate. Sitagliptin phosphate (MK 0431 phosphate) is a potent inhibitor of DPP4 with an IC50 of 19 nM in Caco 2 cell extracts. Product information CAS Number: 1432063 88 1 Molecular Weight: 508. 33 Formula: C16H17F6N5O5P Chemical Name: (3R) 3 amino 1 [3 (trifluoromethyl)(5,5,6,6 H) 5H,6H,7H,8H [1,2,4]triazolo[4,3 a]pyrazin 7 yl] 4 (2,4,5 trifluorophenyl)butan 1 one

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