Pay in 4 interest-free payments of $26.77 Learn more
Ships within 48 hours · Estimated delivery Aug 16 - Aug 21
5S)-3-{[(2S
InChi: InChI=1S/C18H15ClN2O2S/c1-12-3-4-14(10-20-12)18-17(9-15(19)11-21-18)13-5-7-16(8-6-13)24(2
MEK162 was orally dosed to mice at 3-30 mg/kg once per day
23 nM for NIK-catalyzed hydrolysis of ATP to ADP
Formula: C33H49ClN2O6
PI-3065 Catalog No.:M8668-10 5S)-3-{[(2SPI3065 is a p110 isoform of phosphoinositide 3 OH kinase (PI(3)K) inhibitor. Inhibitors against the p110 isoform of phosphoinositide 3 OH kinase (PI(3)K) have shown remarkable therapeutic efficacy in some human leukaemias. As p110 is primarily expressed in leukocytes, drugs against p110 have not been considered for the treatment of solid tumours. p110 inactivation in regulatory T cells unleashes CD8(+) cytotoxic T cells and induces tumour regression.