IACS-8968 R-enantiomer xylic acid) Smiles: CN1N=CC(NC(=O)C2N=C(SC=2N)C2C(F)=CC=CC=2F)=C1N1CC[C@@H](N)[C@H](F)CC1

Smiles: CN1N=CC(NC(=O)C2N=C(SC=2N)C2C(F)=CC=CC=2F)=C1N1CC[C@@H](N)[C@H](F)CC1

33 mg/mL (167

Chemical Name: bis[({[(2R

iHCK-37 (3-9 μM

CAS Number: 1196109-52-0

IACS-8968 R-enantiomer xylic acid) Smiles: CN1N=CC(NC(=O)C2N=C(SC=2N)C2C(F)=CC=CC=2F)=C1N1CC[C@@H](N)[C@H](F)CC1IACS 8968 (R enantiomer) is the R enantiomer of IACS 8968. IACS 8968 is a dual IDO and TDO inhibitor, with pIC50s of 6. 43 for IDO and <5 for TDO, respectively. Product information CAS Number: 2239305 67 8 Molecular Weight: 381. 35 Formula: C17H18F3N5O2 Chemical Name: (5R) 6,6 dimethyl 8 [7 (trifluoromethyl)imidazo[1,5 a]pyridin 5 yl] 1,3,8 triazaspiro[4. 5]decane 2,4 dione Smiles: CC1(C)CN(CC[C@]21NC(=O)NC2=O)C1=CC(=CC2=CN=CN21)C(F)(F)F InChiKey: