CEP-28122 mesylate salt Catalog No.:M20814-C QS11 binds and inhibits the

QS11 binds and inhibits the GTPase activating protein of ARFGAP1

Chemical Name: L-Alanyl-L-alanyl-L-valyl-L-alanyl-L-leucyl-L-leucyl-L-prolyl-L-alanyl-L-valyl-L-leucyl-L-leucyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-prolyl-L-valyl-L-glutaminyl-L-arginyl-L-lysyl-L-arginyl-L-arginyl-L-lysyl-L-alanyl-L-leucyl-L-proline

Formula: C25H29ClF3N5O9

InChiKey: CJDRUOGAGYHKKD-RQBLFBSQSA-N

small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase

CEP-28122 mesylate salt Catalog No.:M20814-C QS11 binds and inhibits theCEP 28122 mesylate salt, a diaminopyrimidine derivative, is a potent, selective, and orally bioavailable ALK inhibitor, with an IC50 value of 1. 9 nM for recombinant ALK kinase activity. CEP 28122 has antitumor activity in experimental models of ALK positive human cancers. CEP 28122 mesylate salt has good pharmacodynamic and pharmacokinetic activity. Product information CAS Number: 2070009 30 0 Molecular Weight: 635. 17 Formula: C29H39ClN6O6S Chemical